Iovance recently announced their completion of the BLA to the FDA for Lifeleucel in Metastatic Melanoma. See press release here. Data for this study published in JCO here! This is a treatment protocol that we at the Orlando Health Cancer Institute have been very proud to have enroll and treat melanoma folks as well other …
Research Advances
Stay Informed About the Latest Oncology Breakthroughs
Explore the forefront of oncological research with our “Research Advances” category. Discover cutting-edge studies, innovative treatments, and scientific insights into cancer. Stay up-to-date with the latest breakthroughs and advancements in the field of oncology to make informed decisions about your health or that of your loved ones. Dive into the world of scientific progress and gain a deeper understanding of how research is shaping the future of cancer care.
I have sponsor, regulatory and IRB permissions/approval to post this blog publicly on social media. I am very excited about this protocol using intra-tumoral modified Polio viral therapy for patients with metastatic melanomas. Lerapolturev (formerly known as PVSRIPO) is a type of oncolytic virus that is currently being studied for the treatment of melanoma. An …
Melanoma is a tricky disease that often comes back when you least expect it. Just like a sneaky burglar who breaks into your house when you’re not looking, melanoma can hide in your body and then suddenly reappear. That’s exactly what happened to one of my patients, who thought she had beaten the disease years …
I have sponsor, regulatory and IRB permissions/approval to post this blog publicly on social media. I am very excited about this protocol using TILs for breast cancer, colorectal, uveal melanomas, and now also inclusive of cutaneous melanoma, nsclc, head/neck carcinoma. Further details can be found here at the sponsor site and at clinical trials.gov. Adoptive …
As an oncologist, I have seen the importance of using circulating tumor DNA (ctDNA) analysis in cancer diagnosis and treatment. ctDNA is a simple blood test that can provide valuable information about a patient’s cancer, making it a valuable tool in the fight against this disease. Signatera is a technology developed by Natera that uses tumor-informed …
Imagine if your body had superpowers to fight cancer! Well, that’s exactly what a new treatment called Intratumoral therapy does. By giving your body the tools it needs to attack cancer cells, this treatment is changing the game for patients with unresectable or metastatic melanoma. Some of the treatments are directly killing cancer cells itself …
Metastatic gastric cancer, also known as stage IV gastric cancer, is a serious and advanced form of the disease in which the cancer has spread beyond the stomach to other parts of the body. The current standard of care for patients with metastatic gastric cancer includes chemotherapy, Her2 targeted therapy and immunotherapy. However, there remains …
KRAS is a gene that plays a key role in the growth and division of cells. Mutations in the KRAS gene can cause cancer, and one particular mutation called KRAS G12C occurs in about 1-2% of pancreatic cancers and 2-4% of colon cancers. These mutations make the cancer resistant to certain treatment options and are …
As a physician, one of the most challenging types of cancer to treat is locally advanced rectal cancer. These tumors have often grown to the point where surgery alone is not enough to remove all of the cancer and prevent recurrence. That’s why the standard of care for these patients is a treatment approach called …
Cancer treatment is never easy. Between appointments, medications and side effects, there’s a lot to navigate. Immunotherapy, also called immuno-oncology, offers an approach that is promising for many types of cancer. But what exactly is this treatment and how do you know if it’s right for you? How Immunotherapy Works Called a biological therapy, immunotherapy is a …