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Melanoma

Explore the world of melanoma, a formidable form of skin cancer, through our dedicated “Melanoma” subcategory. Gain valuable insights into the causes, risk factors, and early detection of melanoma. Dive deep into the latest advancements in melanoma treatment options, including surgical interventions, immunotherapy, and targeted therapies. Whether you’re seeking information for prevention, diagnosis, or support, this subcategory is your trusted resource for comprehensive knowledge about melanoma. Together, we’ll navigate this journey toward melanoma awareness and effective management.

ESMO 2026 – NADINA Neoadjuvant Immunotherapy: We Kept the Baby But Are WE Throwing Out the Nursery?

Three-year NADINA data showed something that shouldn’t happen: near-complete responders did substantially worse than partial responders — 62.3% versus 87.5% recurrence-free survival. One design feature separates NADINA from every neoadjuvant melanoma trial before it. NADINA mandated full lymph node dissection in every patient; PRADO left the basin alone in major responders. I think that may be the explanation, and nobody raised it.

ESMO 2026, Day 1: What’s New in Melanoma

Four randomized trials and one excellent symposium defined day one of the melanoma program at ESMO 2026 in Madrid: an oral HDAC inhibitor added to nivolumab, a BRAF/MEK-plus-immunotherapy triplet, two trials pushing TIL cell therapy earlier and lighter, and a landscape in metastatic uveal melanoma that has changed faster than most providers realize. Here is the data as presented, and my take on each.

Third Time’s the Charm

After two rejections, the FDA approved a new melanoma therapy that finally reaches beyond the skin — into the liver, into the lungs. Here’s why the third try worked.

The BRAF Pathway to TIL Program: Why Earlier Planning May Change the Treatment Journey for Melanoma Patients

The BRAF Pathway to TIL Program transforms TIL therapy from a last-minute scramble into a proactive treatment strategy.

The mRNA moment in melanoma: a 5-year update—and a flashback to the COVID era

When science stays the course, time becomes part of the treatment.

Ocular-Sparing Therapy in Uveal Melanoma: A New Era Emerges with Darovasertib

Protecting vision, preserving the person — the promise of ocular-sparing oncology.

A New Chapter in Melanoma Care? Encouraging Phase 3 Results for Cylembio® + Pembrolizumab

When innovation meets immune activation, new possibilities emerge for melanoma care.

TCR Therapy Targets PRAME in Melanoma: Early Results from IMA203 Show Real Promise Presented From ASCO 2025

Targeting PRAME with TCR-T cell therapy may mark a new era for immunotherapy in melanoma and beyond.

Melanoma Highlights from ASCO: Targeted Therapy, Immunotherapy, and Innovations

From early-stage to brain metastases, ASCO’s latest melanoma abstracts spotlight the growing power of targeted and immune-based therapies across disease stages.

Our New Compass in the Fog of Cancer Care: Updates from ASCO 2025

ctDNA is helping us track what truly matters—real-time, personalized signals that guide smarter decisions in cancer care.

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Recent Posts

  • SITC 2026 Phoenix: Notes From the Front Row of Immunotherapies
  • ESMO 2026 – NADINA Neoadjuvant Immunotherapy: We Kept the Baby But Are WE Throwing Out the Nursery?
  • A Cancer Vaccine That Works
  • ESMO 2026, Day 1: What’s New in Melanoma
  • A Year of Firsts, and Day 1 at ESMO in Madrid

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Meet the authors

Dr. Sajeve Thomas
Dr Daniel Landau


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  • Home
  • Blog
    • The essentials
    • Art of Oncology
    • Prevention and Healthy Lifestyle
    • Research Advances
    • Navigation Corner
    • Video Library
  • Meet and Greet
    • About Dr Thomas
    • About Dr Landau
  • Ask MedOncMD?
  • 🧠 How I Create My Blog Posts