Uveal melanoma, a rare and aggressive form of eye cancer, has just witnessed a groundbreaking development in its treatment landscape. The Food and Drug Administration (FDA) recently granted approval to the HEPZATO KIT, an innovative liver-directed therapy that offers new hope to adult patients with uveal melanoma and unresectable hepatic metastases.
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Explore the forefront of oncological research with our “Research Advances” category. Discover cutting-edge studies, innovative treatments, and scientific insights into cancer. Stay up-to-date with the latest breakthroughs and advancements in the field of oncology to make informed decisions about your health or that of your loved ones. Dive into the world of scientific progress and gain a deeper understanding of how research is shaping the future of cancer care.
Intratumoral therapies is another class of immunotherapeutics that I often consider especially for folks with limited skin or nodal disease or perhaps deeper oligometastatic disease. I have cutaneous malignancies patients with Melanoma, Cutaneous SCC, Merkel cell and Kaposi sarcomas that have responded to local intratumoral therapies. We’ve seen viral agents like FDA approved TVEC, RP1, …
Myelodysplasia (MDS) is a bone marrow syndrome characterized by the presence of unhealthy (dysplastic) stem cells that displace the healthy ones, disrupting their ability to mature and develop properly. These healthy stem cells are responsible for generating essential components like red blood cells (which transport oxygen), white blood cells (crucial for fighting infections), and platelets (important for clotting). However, the unhealthy cells can suppress the function of the healthy ones, leading to various dysfunctions.
In terms of cancer diagnoses, the more common ones we hear of are cancers such as Leukemia, Lymphoma, melanoma, and breast cancer. But what about Leiomyosarcoma?
Leiomyosarcoma is a rare and aggressive form of cancer that develops in the smooth muscles of the body (i.e. intestines, stomach, uterus, blood vessels).
Hematologists play a pivotal role in addressing various non-cancerous hematological conditions, alleviating patient concerns about being associated solely with cancer care. Many patients are unaware that hematologists are involved in treating a range of benign conditions, including: 1. Anemia: Anemia, characterized by low hemoglobin levels, can stem from various causes such as iron deficiency, inadequate …
One of the most vivid metaphors for chemotherapy is that of a bomb: it obliterates both good and bad cells, with the hope that only the good ones regenerate. While traditional chemotherapy remains a significant tool in cancer treatment, there’s been a recent shift towards more precise therapies that selectively target cancer cells. In the …
In a recent heartfelt letter to viewers, esteemed news anchor Greg Warmoth bravely opened about his lip cancer diagnosis. This news serves as a reminder of the importance of raising awareness about this particular form of cancer, its typical prognosis, available treatment options, and preventive measures that can be taken. Understanding Lip Cancer: Cutaneous squamous cell cancer is a relatively …
Here’s an interested case of a patient with MCC that I saw this past week. While I’d like to consider systemic immunotherapy with PD1 or dual checkpoint inhibitors, chemotherapy, clinical trial with MDNA or TLR9 agonist/PD1, this patient’s disease was limited to the skin alone. Could we do something different and perhaps with less risk …
Navigating the tumultuous waters of a cancer diagnosis can be a daunting task for any patient. Add to this a significant cardiac issue or a serious neurological complication, and the situation becomes even more intricate. This delicate dance, where life-threatening conditions intersect, highlights the need for truly multidisciplinary care. It’s a timely reminder that medicine …
This is a new clinical trial using Tebentafusp alone or in combination with Pembrolizumab is now open and actively enrolling at the Orlando Health Cancer Institute for patients dealing with Metastatic Cutaneous Melanoma. Tebentafusp is currently FDA approved for all patients with Metastatic Uveal Melanoma. Detailed information can be found here at clinicaltrials.gov and NEJM …