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Varied Cancer Perspectives

Explore a comprehensive range of insights and information within our ‘Varied Cancer Perspectives’ category. From melanoma to breast cancer, colorectal cancer to sarcoma, and beyond, this diverse collection delves into the multifaceted world of oncology. Gain a nuanced understanding of different cancer types, treatments, and the latest advancements in research. Whether you’re seeking knowledge on pediatric oncology, uveal melanoma, or desmoid tumors, our curated content provides a holistic view, offering valuable perspectives to empower and inform those navigating the complexities of cancer care. Join us on a journey through varied perspectives, ensuring a well-rounded understanding of the ever-evolving landscape of cancer.

Targeting Urothelial Cancer: EV 103 Study Results

One of the most vivid metaphors for chemotherapy is that of a bomb: it obliterates both good and bad cells, with the hope that only the good ones regenerate. While traditional chemotherapy remains a significant tool in cancer treatment, there’s been a recent shift towards more precise therapies that selectively target cancer cells. In the …

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Shining a Spotlight on Lip Cancer: Understanding and Advocacy

In a recent heartfelt letter to viewers, esteemed news anchor Greg Warmoth bravely opened about his lip cancer diagnosis. This news serves as a reminder of the importance of raising awareness about this particular form of cancer, its typical prognosis, available treatment options, and preventive measures that can be taken. Understanding Lip Cancer: Cutaneous squamous cell cancer is a relatively …

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TVEC: A Promising Solution for Skin-Limited Merkel Cell Carcinoma?

Here’s an interested case of a patient with MCC that I saw this past week. While I’d like to consider systemic immunotherapy with PD1 or dual checkpoint inhibitors, chemotherapy, clinical trial with MDNA or TLR9 agonist/PD1, this patient’s disease was limited to the skin alone. Could we do something different and perhaps with less risk …

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Emerging Clinical Trial: Tebentafusp Regimen in Previously Treated Advanced Cutaneous Melanoma

Emerging Clinical Trial: Tebentafusp Regimen in Previously Treated Advanced Cutaneous Melanoma

This is a new clinical trial using Tebentafusp alone or in combination with Pembrolizumab is now open and actively enrolling at the Orlando Health Cancer Institute for patients dealing with Metastatic Cutaneous Melanoma. Tebentafusp is currently FDA approved for all patients with Metastatic Uveal Melanoma. Detailed information can be found here at clinicaltrials.gov and NEJM …

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A Promising New Addition to GIST Treatment Strategies: 2nd line Clinical Trial Open

A Promising New Addition to GIST Treatment Strategies: 2nd line Clinical Trial Open

Article written by one of our Melanoma/Sarcoma Clinical Trial Coordinators Chloe Caldwell to a target audience of healthcare providers regarding a new ongoing protocol for patients dealing with GIST open globally and at the Orlando Health Cancer Institute. All information posted here is publicly available here. Gastrointestinal Stromal Tumors (GIST) constitute a category of soft …

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Pioneering Therapies Unveil New Hope for High-Risk Melanoma Patients

Pioneering Therapies Unveil New Hope for High-Risk Melanoma Patients

ASCO 2023 was an incredible conference and I had completely enjoyed the networking, presentations, and evening meetings. Here are two melanoma clinical trials that we had also participated in enrollment at the Orlando Health Cancer Institute. It is incredibly exciting to see patients do better with improved responses as well as improved odds of not …

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A Revolutionary Paradigm Shift to Rectal Cancer Treatment: Insights from the PROSPECT Trial Presented at ASCO 2023

A Revolutionary Paradigm Shift to Rectal Cancer Treatment: Insights from the PROSPECT Trial Presented at ASCO 2023

ASCO 2023 was a ton of fun and lot of learning. In the coming weeks, I’ll share select abstracts that I thought were most important. This article discusses data from a groundbreaking PROSPECT trial which was presented as a Plenary topic at Chicago and published in NEJM last week. Ultimately, this creates more treatment options …

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TILVANCE-301 Phase 3 Trial: Cellular Therapy and Pembrolizumab in Advanced Melanoma

TILVANCE-301 Phase 3 Trial: Cellular Therapy and Pembrolizumab in Advanced Melanoma

Replaying this post as a reminder that this study is enrolling at multiple sites globally. More detailed information can also be seen here at clinicaltrials.gov as well as the sponsor Iovance. All information and data stated in this article are available publicly through online resources that I’ve also linked below for reference. This new trial …

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From Pandemic Response to Cancer Prevention Breakthrough: The Promise of mRNA Vaccine in Malignant Melanoma

From Pandemic Response to Cancer Prevention Breakthrough: The Promise of mRNA Vaccine in Malignant Melanoma

mRNA technology has revolutionized the world of medicine. Known for its role in the creation of COVID-19 vaccines, mRNA has been lauded as a game-changer in the fight against infectious diseases. But mRNA’s impact extends far beyond pandemic control. It’s now making waves in another critical area of healthcare: cancer treatment and prevention.  mRNA stands …

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Adaptimmune: Engineering T-Cell Receptors to Target Cancer Cells Clinical Trial at the Orlando Health Cancer Institute

Adaptimmune: Engineering T-Cell Receptors to Target Cancer Cells Clinical Trial at the Orlando Health Cancer Institute

I am really excited about this new protocol specifically for patients with MAGE4+ HLA restricted SPEAR TILs for Metastatic Melanoma, Non-small Cell Lung Cancer, Head Neck cancer, Ovarian, Endometrial, and Urothelial cancers. The Gastric and Esophageal Cancer cohorts are closed. The social media material seen here was approved both the sponsor and IRB. Please contact …

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Categories

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Meet the authors

Dr. Sajeve Thomas
Dr Daniel Landau


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  • Home
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    • The essentials
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    • About Dr Thomas
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  • Ask MedOncMD?
  • 🧠 How I Create My Blog Posts