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Research Advances

Stay Informed About the Latest Oncology Breakthroughs

Explore the forefront of oncological research with our “Research Advances” category. Discover cutting-edge studies, innovative treatments, and scientific insights into cancer. Stay up-to-date with the latest breakthroughs and advancements in the field of oncology to make informed decisions about your health or that of your loved ones. Dive into the world of scientific progress and gain a deeper understanding of how research is shaping the future of cancer care.

GRANITE Immunotherapy Offers Hope for MSS Metastatic Colorectal Cancer: Improving Progression-Free Survival with Neoantigen-Directed Therapy

Immunotherapy has made significant strides in cancer treatment, but microsatellite stable (MSS) metastatic colorectal cancer (mCRC) has long posed a challenge due to its resistance to immune-based therapies. However, promising results from a recent phase 2/3 trial have shown that the individualized neoantigen-directed immunotherapy, GRANITE, may change the outlook for patients with MSS mCRC. This innovative therapy, combined …

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FDA Approves Inavolisib for Endocrine-Resistant Advanced Breast Cancer: A New Option for PIK3CA-Mutated Patients

On October 10, 2024, the FDA approved a new and promising treatment for patients with advanced breast cancer: inavolisib (Itovebi), in combination with palbociclib and fulvestrant. This new approval offers fresh hope for patients with endocrine-resistant, PIK3CA-mutated, hormone receptor (HR)-positive, and HER2-negative breast cancer, especially those whose disease has progressed after endocrine therapy. The approval also includes the FoundationOne Liquid CDx assay, a diagnostic test used to …

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New Hope for Limited-Stage Small-Cell Lung Cancer: Durvalumab Shows Promising Results After Chemoradiotherapy

Small-cell lung cancer (SCLC) is a notoriously aggressive form of lung cancer, making up about 15% of all lung cancer cases. While treatments have made strides in extensive-stage SCLC, limited-stage SCLC has seen few advancements in decades—until now. A new clinical trial published in the New England Journal of Medicine has revealed promising results with the use …

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A Promising New Treatment for Metastatic Breast Cancer: Exploring Bria-IMT™ and Its Impact

A Promising New Treatment for Metastatic Breast Cancer: Exploring Bria-IMT™ and Its Impact When battling metastatic breast cancer, finding effective treatment options can feel like an uphill battle, especially when cancer has spread to other areas, like the brain. But new hope is on the horizon. A groundbreaking therapy called Bria-IMT™ is showing promising results in clinical …

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Immunotherapy in Breast Cancer: A Modern Approach to Treatment

October is Breast Cancer Awareness Month, a time dedicated to spreading knowledge, supporting research, and empowering patients and healthcare providers alike. Throughout the month, we’ll explore various critical aspects of breast cancer care. In this post, we focus on the current role of immunotherapy in treatment and encourage both patients and providers to consider clinical …

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A Promising New Treatment for Chronic Myeloid Leukemia: What You Should Know About Asciminib

A recent New England Journal of Medicine study introduces asciminib, a new treatment for Chronic Myeloid Leukemia (CML) that shows improved effectiveness and fewer side effects compared to current therapies. This post will explain the study’s findings and what they mean for patients and caregivers, highlighting how asciminib could offer a better option for those newly diagnosed with …

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Immunotherapy Post-Surgery Improves Survival in High-Risk Bladder Cancer

Sophia’s Story I’ll never forget the day I met Sophia. She sat in my clinic, a mother of two and a dedicated teacher, but her eyes were clouded with fear. When she first received the news that she had high-risk bladder cancer, she told me she felt like the ground had shifted beneath her feet. …

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Jimmy Carter and the Power of Immunotherapy: A Shift from Palliative to Curative Intent

When I meet new patients diagnosed with Stage IV metastatic melanoma, I often mention the name Jimmy Carter. It’s a name most people recognize, and his survival story is nothing short of remarkable—especially considering he will soon celebrate his 100th birthday. Like many of my patients, Carter was diagnosed with Stage IV melanoma, with metastatic …

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Advancing Sickle Cell Disease Care: A New Era of Research and Treatment

Gene Therapy: A Promising Future As I continue to highlight key aspects of SCD this September, I will shift the focus to the exciting advancements in research and treatment. Recent breakthroughs offer new hope and possibilities for individuals living with this condition. In this installment, we’ll explore the latest research developments, including innovative therapies and …

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New Treatment Option for Advanced Leiomyosarcoma: Doxorubicin and Trabectedin Combination Therapy

A recent article published in the New England Journal of Medicine (NEJM) demonstrated higher response, longer progression free survival and overall survival in patients with unresectable or metastatic leiomyosarcoma.  A treatment protocol that we’ve been doing for at least 1-2 years prior given the known higher response rate reported at conferences.  This is a new …

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Categories

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Meet the authors

Dr. Sajeve Thomas
Dr Daniel Landau


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  • Home
  • Blog
    • The essentials
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    • Research Advances
    • Navigation Corner
    • Video Library
  • Meet and Greet
    • About Dr Thomas
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  • đź§  How I Create My Blog Posts