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Merkel Cell Carcinoma: Shining a Light on the Darkest of Skin Cancers

Merkel Cell Carcinoma: Shining a Light on the Darkest of Skin Cancers

Merkel cell carcinoma (MCC) is the unsung villain of the skin cancer world – rare, aggressive, and often flying under the radar. MCC is a neuroendocrine skin cancer that usually rears its ugly head as a firm, painless nodule on sun-exposed areas of the skin. Risk factors for this sneaky skin invader include advanced age, …

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Navigating Oligometastatic Disease: From Stage IV to Remission, A Personalized Approach to Oligometastatic Cancer Treatment

Navigating Oligometastatic Disease: From Stage IV to Remission, A Personalized Approach to Oligometastatic Cancer Treatment

“How am I doing?”, asked one of my colorectal patients. Ten years ago, I first met John (name changed for privacy), a warm and spirited individual diagnosed with stage 3 colon cancer. After undergoing surgical resection of the primary colon tumor and six months of standard adjuvant chemotherapy with mFOLFOX, John and I optimistically looked …

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New Trial at the Orlando Health Cancer Institute Using Interleukin-2 Superkine (MDNA11) to treat multiple solid tumor types

New Trial at the Orlando Health Cancer Institute Using Interleukin-2 Superkine (MDNA11) to treat multiple solid tumor types

New and exciting immunotherapeutic trial for multiple cancer subtypes. Article written by our senior research coordinator Karin Donaldson. Consider trials earlier in the course in patients with unresectable or metastatic cancer whenever possible. I have sponsor and IRB approval to place this article on this blog! More detail information can be found at MDNA and …

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The Oncologist’s Toolbox: Exploring the Cutting-Edge Techniques of Genetic Testing in Cancer Treatment

The Oncologist’s Toolbox: Exploring the Cutting-Edge Techniques of Genetic Testing in Cancer Treatment 

Imagine you’re driving your car when suddenly, it begins to malfunction – sputtering, stalling, and generally misbehaving. What’s going on under the hood? If you’re anything like most people, you’d probably take your car to a mechanic who can identify the faulty parts and get you back on the road. In many ways, oncologists can …

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The Gut Feeling You Can’t Ignore: How H. Pylori and Your Genetics Can Gang Up on You!

The Gut Feeling You Can’t Ignore: How H. Pylori and Your Genetics Can Gang Up on You!  

New article published in the NEJM confirming the high risk for gastric cancer with susceptible folks with H. Pylori infections. Another reason for me to check dna platforms such as 23andme! As a physician who not too long ago discovered my own asymptomatic H. pylori infection, I couldn’t help but wonder if there was more …

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Navigating the Complexities of Cancer Care: The Navigator’s Role

Navigating the Complexities of Cancer Care: The Navigator’s Role

This post was written by our melanoma/sarcoma nurse navigator Ashlee Jones. She is highly respected by all members of my team to include the nurses, pharmacist, staff, research team, and physicians! I’ve always felt that new patients diagnosed with cancer can initially have a rough start in the journey given the new diagnosis, the array …

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Catching Cancer Before It Spreads: The Promise of ctDNA in Malignant Melanoma

Catching Cancer Before It Spreads: The Promise of ctDNA in Malignant Melanoma

A recent publication by Dr Eroglu et al. in Cancer can be found here! Hope this articles helps! As an oncologist, my days are filled with fascinating and challenging cases, but one recent patient in particular caught my attention. He was a young man who had just undergone surgery to remove high-risk Stage IIC malignant …

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Navigating the Clinical Trial Labyrinth: A Step by Step Guide Searching Clinical Trials.gov and at the Orlando Health Cancer Institute

Navigating the Clinical Trial Labyrinth: A Step by Step Guide Searching Clinical Trials.gov and at the Orlando Health Cancer Institute

Often I am asked about clinical trial options at our site or perhaps at other institutions. It is important for patients and families that they consider clinical trials at any point in their treatment journey. For most medical oncologist, it is preferred to consider a trial option if one is available to them and the …

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Tackling Tumors with T Cells: Lifileucel’s Revolutionary Approach to Melanoma

Tackling Tumors with T Cells: Lifileucel’s Revolutionary Approach to Melanoma

Iovance recently announced their completion of the BLA to the FDA for Lifeleucel in Metastatic Melanoma. See press release here. Data for this study published in JCO here! This is a treatment protocol that we at the Orlando Health Cancer Institute have been very proud to have enroll and treat melanoma folks as well other …

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The Balancing Act of Cancer Surveillance: Insights from an Oncologist

As an oncologist, I see a lot of patients who are concerned about their health and want to do everything they can to stay on top of their cancer. One patient that comes to mind is a woman who I saw the other day with stage 1 rectal cancer treated with a trans anal excision …

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Recent Posts

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  • The TIL Journey: From a Medical Oncologist’s Perspective
  • The mRNA moment in melanoma: a 5-year update—and a flashback to the COVID era
  • Emerging Data in Intratumoral Immunotherapy: Replimmune’s RP1 + Nivolumab in Non‑Melanoma Skin Cancers and Acral Melanoma

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Dr. Sajeve Thomas
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    • The essentials
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