MedOncMD

To provide the information your oncologist is not telling you or doesn't have the time to!

Myelodysplasia (MDS) is a bone marrow syndrome characterized by the presence of unhealthy (dysplastic) stem cells that displace the healthy ones, disrupting their ability to mature and develop properly. These healthy stem cells are responsible for generating essential components like red blood cells (which transport oxygen), white blood cells (crucial for fighting infections), and platelets (important for clotting). However, the unhealthy cells can suppress the function of the healthy ones, leading to various dysfunctions.

Assisting Red Blood Cell Growth

Myelodysplasia (MDS) is a bone marrow syndrome characterized by the presence of unhealthy (dysplastic) stem cells that displace the healthy ones, disrupting their ability to mature and develop properly. These healthy stem cells are responsible for generating essential components like red blood cells (which transport oxygen), white blood cells (crucial for fighting infections), and platelets (important for clotting). However, the unhealthy cells can suppress the function of the healthy ones, leading to various dysfunctions.

Dacarbazine, referred to as DTIC, is a chemotherapy administered intravenously every 3 weeks. Unesbulin is a novel, oral drug, administered twice weekly and is currently being researched in the treatment of advanced solid tumors. In this case, it is being studied in conjunction with DTIC for treatment of metastatic or unresectable, relapsed or refractory Leiomyosarcoma. Participants can be randomized to receive either DTIC with Unesbulin or DTIC with placebo.  

About Leiomyosarcoma – A look at new advances by Chloe Caldwell

In terms of cancer diagnoses, the more common ones we hear of are cancers such as Leukemia, Lymphoma, melanoma, and breast cancer. But what about Leiomyosarcoma?

Leiomyosarcoma is a rare and aggressive form of cancer that develops in the smooth muscles of the body (i.e. intestines, stomach, uterus, blood vessels).

Facing the Unknown: Decoding a Mysterious Axillary Adenopathy

Navigating the complex realm of oncology often involves a blend of clinical expertise, investigative curiosity, and intuitive sensitivity. A recent encounter with a patient, previously diagnosed with a sizable axillary adenopathy considered “benign”, reinforces the necessity of approaching medical puzzles with an open mind and meticulous attention to detail. Earlier this year, a patient was …

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Benign Hematology: Beyond Cancer Concerns

Hematologists play a pivotal role in addressing various non-cancerous hematological conditions, alleviating patient concerns about being associated solely with cancer care. Many patients are unaware that hematologists are involved in treating a range of benign conditions, including: 1. Anemia: Anemia, characterized by low hemoglobin levels, can stem from various causes such as iron deficiency, inadequate …

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Targeting Urothelial Cancer: EV 103 Study Results

One of the most vivid metaphors for chemotherapy is that of a bomb: it obliterates both good and bad cells, with the hope that only the good ones regenerate. While traditional chemotherapy remains a significant tool in cancer treatment, there’s been a recent shift towards more precise therapies that selectively target cancer cells. In the …

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Shining a Spotlight on Lip Cancer: Understanding and Advocacy

In a recent heartfelt letter to viewers, esteemed news anchor Greg Warmoth bravely opened about his lip cancer diagnosis. This news serves as a reminder of the importance of raising awareness about this particular form of cancer, its typical prognosis, available treatment options, and preventive measures that can be taken. Understanding Lip Cancer: Cutaneous squamous cell cancer is a relatively …

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TVEC: A Promising Solution for Skin-Limited Merkel Cell Carcinoma?

Here’s an interested case of a patient with MCC that I saw this past week. While I’d like to consider systemic immunotherapy with PD1 or dual checkpoint inhibitors, chemotherapy, clinical trial with MDNA or TLR9 agonist/PD1, this patient’s disease was limited to the skin alone. Could we do something different and perhaps with less risk …

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Telehealth Revolutionizing Healthcare Delivery By Dr Danny Landau

Dr Landau led the Telehealth initiative at the Orlando Health Cancer Institute which became a proven necessity for our patient population not only at the peak of the pandemic but to this very day. Envisioning a future where expert-level healthcare is accessible to individuals regardless of their location, the concept of telehealth has emerged as …

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The Critical Interplay: When Oncology Meets Cardiology and Neurosurgery

The Critical Interplay: When Oncology Meets Cardiology and Neurosurgery

Navigating the tumultuous waters of a cancer diagnosis can be a daunting task for any patient. Add to this a significant cardiac issue or a serious neurological complication, and the situation becomes even more intricate. This delicate dance, where life-threatening conditions intersect, highlights the need for truly multidisciplinary care. It’s a timely reminder that medicine …

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