Emerging data from ESMO 2025 highlight encouraging activity of the oncolytic virus RP1 plus nivolumab across several advanced non‑melanoma skin cancers, especially in PD‑1 naive and refractory settings.
Skin Cancer
Uncover essential insights into the world of skin cancer within our dedicated ‘Skin Cancer’ subcategory. From melanoma to basal cell carcinoma, this specialized section delves into the complexities of skin-related malignancies. Explore informative articles, cutting-edge research updates, and practical resources aimed at fostering awareness and understanding of skin cancer. Whether you’re seeking guidance on prevention, early detection, or the latest advancements in treatment options, our ‘Skin Cancer’ subcategory is your go-to source. Empowering individuals with knowledge, we navigate through the nuances of skin cancer, providing a comprehensive resource for patients, caregivers, and those committed to skin health. Join us on a journey towards informed decision-making and proactive skin care in the realm of dermatologic oncology
A firewall against relapse — adjuvant immunotherapy steps into the spotlight for resected Merkel cell carcinoma.
Cutaneous squamous cell carcinoma (CSCC) is one of the most common skin cancers, with cases ranging from easily treatable localized lesions to aggressive forms that can metastasize or become life-threatening. On December 13, 2024, the FDA approved cosibelimab-ipdl (Unloxcyt), a PD-L1 blocking antibody, offering new hope for adults with metastatic CSCC (mCSCC) or locally advanced …
Intratumoral therapies is another class of immunotherapeutics that I often consider especially for folks with limited skin or nodal disease or perhaps deeper oligometastatic disease. I have cutaneous malignancies patients with Melanoma, Cutaneous SCC, Merkel cell and Kaposi sarcomas that have responded to local intratumoral therapies. We’ve seen viral agents like FDA approved TVEC, RP1, …
In a recent heartfelt letter to viewers, esteemed news anchor Greg Warmoth bravely opened about his lip cancer diagnosis. This news serves as a reminder of the importance of raising awareness about this particular form of cancer, its typical prognosis, available treatment options, and preventive measures that can be taken. Understanding Lip Cancer: Cutaneous squamous cell cancer is a relatively …
Here’s an interested case of a patient with MCC that I saw this past week. While I’d like to consider systemic immunotherapy with PD1 or dual checkpoint inhibitors, chemotherapy, clinical trial with MDNA or TLR9 agonist/PD1, this patient’s disease was limited to the skin alone. Could we do something different and perhaps with less risk …
Merkel cell carcinoma (MCC) is the unsung villain of the skin cancer world – rare, aggressive, and often flying under the radar. MCC is a neuroendocrine skin cancer that usually rears its ugly head as a firm, painless nodule on sun-exposed areas of the skin. Risk factors for this sneaky skin invader include advanced age, …
When a lump or bump is found on a physical exam or a tumor/nodule/lesion is seen on imaging, it can be concerning. But how do we know for sure if it’s a malignant tumor vs a benign tumor? The answer is a biopsy. A biopsy is a procedure in which a small piece of the …
In Florida, we love our golf. With over 1,200 courses throughout the state, Florida can make a strong claim for Golf Capital of the World. Not Just Sunburn While no one would argue that golf isn’t a fun pastime, our year-round access to the sun-drenched links comes with an increased risk for a serious and …