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Leiomyosarcoma

New Treatment Option for Advanced Leiomyosarcoma: Doxorubicin and Trabectedin Combination Therapy

A recent article published in the New England Journal of Medicine (NEJM) demonstrated higher response, longer progression free survival and overall survival in patients with unresectable or metastatic leiomyosarcoma.  A treatment protocol that we’ve been doing for at least 1-2 years prior given the known higher response rate reported at conferences.  This is a new …

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Dacarbazine, referred to as DTIC, is a chemotherapy administered intravenously every 3 weeks. Unesbulin is a novel, oral drug, administered twice weekly and is currently being researched in the treatment of advanced solid tumors. In this case, it is being studied in conjunction with DTIC for treatment of metastatic or unresectable, relapsed or refractory Leiomyosarcoma. Participants can be randomized to receive either DTIC with Unesbulin or DTIC with placebo.  

About Leiomyosarcoma – A look at new advances by Chloe Caldwell

In terms of cancer diagnoses, the more common ones we hear of are cancers such as Leukemia, Lymphoma, melanoma, and breast cancer. But what about Leiomyosarcoma?

Leiomyosarcoma is a rare and aggressive form of cancer that develops in the smooth muscles of the body (i.e. intestines, stomach, uterus, blood vessels).

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Meet the authors

Dr. Sajeve Thomas
Dr Daniel Landau


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