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Biliary tract cancer

FDA Accelerates Approval of Zanidatamab-hrii for HER2-Positive Biliary Tract Cancer

On November 20, 2024, the FDA granted accelerated approval to zanidatamab-hrii (Ziihera), a bispecific HER2-directed antibody, for the treatment of previously treated, unresectable, or metastatic HER2-positive biliary tract cancer (BTC). This decision brings new hope for patients battling this aggressive and hard-to-treat disease, offering a targeted option for a population with limited therapeutic choices. The …

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New Hope for Limited-Stage Small-Cell Lung Cancer: Durvalumab Shows Promising Results After Chemoradiotherapy

Small-cell lung cancer (SCLC) is a notoriously aggressive form of lung cancer, making up about 15% of all lung cancer cases. While treatments have made strides in extensive-stage SCLC, limited-stage SCLC has seen few advancements in decades—until now. A new clinical trial published in the New England Journal of Medicine has revealed promising results with the use …

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FDA Approves Pembrolizumab with Chemotherapy for Biliary Tract Cancer: A Promising Breakthrough

FDA Approves Pembrolizumab with Chemotherapy for Biliary Tract Cancer: A Promising Breakthrough

by Sajeve Thomas,  MD, Oncologist Biliary tract cancer (BTC), a rare and aggressive form of cancer affecting the bile ducts, gallbladder, and liver, has historically been challenging to treat. However, there is hope on the horizon with the recent FDA approval of pembrolizumab (Keytruda, Merck) in combination with chemotherapy. This groundbreaking development offers new possibilities …

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