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New Treatments and Therapies

Here, we delve into the dynamic world of cutting-edge cancer treatments and therapies. Stay informed about groundbreaking advancements in cancer care, from emerging therapies to novel treatment modalities. Discover how science and technology are shaping the future of oncology, offering new hope and possibilities to those affected by cancer. Join us as we explore innovative approaches that hold the promise of brighter tomorrows for patients and their families.

GRANITE Immunotherapy Offers Hope for MSS Metastatic Colorectal Cancer: Improving Progression-Free Survival with Neoantigen-Directed Therapy

Immunotherapy has made significant strides in cancer treatment, but microsatellite stable (MSS) metastatic colorectal cancer (mCRC) has long posed a challenge due to its resistance to immune-based therapies. However, promising results from a recent phase 2/3 trial have shown that the individualized neoantigen-directed immunotherapy, GRANITE, may change the outlook for patients with MSS mCRC. This innovative therapy, combined …

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FDA Approves Inavolisib for Endocrine-Resistant Advanced Breast Cancer: A New Option for PIK3CA-Mutated Patients

On October 10, 2024, the FDA approved a new and promising treatment for patients with advanced breast cancer: inavolisib (Itovebi), in combination with palbociclib and fulvestrant. This new approval offers fresh hope for patients with endocrine-resistant, PIK3CA-mutated, hormone receptor (HR)-positive, and HER2-negative breast cancer, especially those whose disease has progressed after endocrine therapy. The approval also includes the FoundationOne Liquid CDx assay, a diagnostic test used to …

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A Promising New Treatment for Chronic Myeloid Leukemia: What You Should Know About Asciminib

A recent New England Journal of Medicine study introduces asciminib, a new treatment for Chronic Myeloid Leukemia (CML) that shows improved effectiveness and fewer side effects compared to current therapies. This post will explain the study’s findings and what they mean for patients and caregivers, highlighting how asciminib could offer a better option for those newly diagnosed with …

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Immunotherapy Post-Surgery Improves Survival in High-Risk Bladder Cancer

Sophia’s Story I’ll never forget the day I met Sophia. She sat in my clinic, a mother of two and a dedicated teacher, but her eyes were clouded with fear. When she first received the news that she had high-risk bladder cancer, she told me she felt like the ground had shifted beneath her feet. …

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Advancing Sickle Cell Disease Care: A New Era of Research and Treatment

Gene Therapy: A Promising Future As I continue to highlight key aspects of SCD this September, I will shift the focus to the exciting advancements in research and treatment. Recent breakthroughs offer new hope and possibilities for individuals living with this condition. In this installment, we’ll explore the latest research developments, including innovative therapies and …

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New Treatment Option for Advanced Leiomyosarcoma: Doxorubicin and Trabectedin Combination Therapy

A recent article published in the New England Journal of Medicine (NEJM) demonstrated higher response, longer progression free survival and overall survival in patients with unresectable or metastatic leiomyosarcoma.  A treatment protocol that we’ve been doing for at least 1-2 years prior given the known higher response rate reported at conferences.  This is a new …

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Osimertinib Emerges as Promising Maintenance Therapy in Stage III EGFR-Mutated NSCLC: Insights from the LAURA Phase III Trial

EGFR-Mutated Non-Small Cell Lung Cancer (NSCLC) EGFR (epidermal growth factor receptor) is a protein located on the surface of cells that regulates their growth and division. Mutations in the EGFR gene can lead to uncontrolled cell growth and are commonly found in various cancers, including non-small cell lung cancer (NSCLC). In patients with unresectable stage …

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PERSEUS Trial Results Lead to FDA Approval of Daratumumab-VRD Regimen for Multiple Myeloma

Multiple myeloma (MM) is a type of blood cancer that originates in the plasma cells, which are a type of white blood cell found in the bone marrow. Plasma cells are responsible for producing antibodies that help fight infections. In multiple myeloma, abnormal plasma cells multiply uncontrollably, leading to a range of complications. Key Characteristics …

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From Hope to Reality: FDA Approves Tecelra, a Breakthrough Gene Therapy for Synovial Sarcoma

When it comes to battling a rare and aggressive cancer like synovial sarcoma, the treatment options have often been limited—until now. The FDA’s recent approval of Tecelra (Amafi-Cel), the first gene therapy for adults with metastatic synovial sarcoma, not only provides new hope for patients who’ve exhausted other options but also paves the way for …

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The Potential of Alectinib in Resected Non-Small Cell Lung Cancer: Insights from the ALINA Study

New exciting data published in the NEJM demonstrating improved for a specific subset of lung cancer patients but also demonstrating the power of targeted therapies when we can identify a driver mutation that is sensitive or “actionable” with a treatment to shut down its specific function. Exciting! Non-Small Cell Lung Cancer (NSCLC) represents a significant …

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Meet the authors

Dr. Sajeve Thomas
Dr Daniel Landau


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  • Home
  • Blog
    • The essentials
    • Art of Oncology
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    • Research Advances
    • Navigation Corner
    • Video Library
  • Meet and Greet
    • About Dr Thomas
    • About Dr Landau
  • Ask MedOncMD?
  • đź§  How I Create My Blog Posts