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Immunotherapy

Unleash the power of your body’s immune system in the fight against cancer with our “Immunotherapy” subcategory. Delve into the realm of groundbreaking treatments that empower your immune system to recognize and combat cancer cells. Explore the latest advances in immunotherapy, from checkpoint inhibitors to CAR-T cell therapies, and learn how they are revolutionizing the landscape of cancer treatment. Join us on a journey to understand how harnessing your body’s natural defenses is paving the way for more targeted and effective therapies in the fight against cancer.

The Melanoma Milestone: Celebrating 10 Years of Immunotherapy Success

Stage IV melanoma used to be synonymous with a terminal diagnosis. For years, oncologists faced the grim reality of limited options and poor survival rates for their patients. However, the landscape has changed dramatically over the past decade. Breakthroughs in immunotherapy and clinical research have rewritten the narrative, offering hope to patients and their families. …

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NEJM Study Highlights Breakthrough in MSI-High Colorectal Cancer Treatment with Ipilimumab and Nivolumab

Colorectal cancer remains a significant global health challenge, ranking as the third most common cancer and the second leading cause of cancer-related deaths worldwide. Among metastatic colorectal cancer patients, the subset with microsatellite instability-high (MSI-H) or mismatch-repair–deficient (dMMR) tumors presents unique opportunities for immunotherapy. The recent CheckMate 8HW trial, published in the New England Journal …

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Innovative Advances in Bladder Cancer Treatment: Durvalumab Plus Chemotherapy in the NIAGARA Trial

Bladder cancer, particularly muscle-invasive bladder cancer (MIBC), poses significant treatment challenges due to its high recurrence rate and aggressive nature. Traditionally, neoadjuvant chemotherapy followed by surgery (radical cystectomy) has been the standard of care for cisplatin-eligible patients. However, researchers have been exploring ways to improve outcomes by incorporating immunotherapy into treatment. A recent phase 3 …

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New Horizons in Colon Cancer Treatment: Neoadjuvant Immunotherapy for Mismatch Repair–Deficient High Risk Stage II/III Colon Cancer

Colon cancer treatments have long relied on surgery, chemotherapy, and radiation. However, recent breakthroughs in immunotherapy, particularly for mismatch repair–deficient (dMMR) tumors, are reshaping how certain high-risk cancers are treated. A recent study published in The New England Journal of Medicine provides encouraging data on the effectiveness of neoadjuvant immunotherapy for patients with locally advanced dMMR colon …

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GRANITE Immunotherapy Offers Hope for MSS Metastatic Colorectal Cancer: Improving Progression-Free Survival with Neoantigen-Directed Therapy

Immunotherapy has made significant strides in cancer treatment, but microsatellite stable (MSS) metastatic colorectal cancer (mCRC) has long posed a challenge due to its resistance to immune-based therapies. However, promising results from a recent phase 2/3 trial have shown that the individualized neoantigen-directed immunotherapy, GRANITE, may change the outlook for patients with MSS mCRC. This innovative therapy, combined …

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New Hope for Limited-Stage Small-Cell Lung Cancer: Durvalumab Shows Promising Results After Chemoradiotherapy

Small-cell lung cancer (SCLC) is a notoriously aggressive form of lung cancer, making up about 15% of all lung cancer cases. While treatments have made strides in extensive-stage SCLC, limited-stage SCLC has seen few advancements in decades—until now. A new clinical trial published in the New England Journal of Medicine has revealed promising results with the use …

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A Promising New Treatment for Metastatic Breast Cancer: Exploring Bria-IMT™ and Its Impact

A Promising New Treatment for Metastatic Breast Cancer: Exploring Bria-IMT™ and Its Impact When battling metastatic breast cancer, finding effective treatment options can feel like an uphill battle, especially when cancer has spread to other areas, like the brain. But new hope is on the horizon. A groundbreaking therapy called Bria-IMT™ is showing promising results in clinical …

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Immunotherapy in Breast Cancer: A Modern Approach to Treatment

October is Breast Cancer Awareness Month, a time dedicated to spreading knowledge, supporting research, and empowering patients and healthcare providers alike. Throughout the month, we’ll explore various critical aspects of breast cancer care. In this post, we focus on the current role of immunotherapy in treatment and encourage both patients and providers to consider clinical …

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Jimmy Carter and the Power of Immunotherapy: A Shift from Palliative to Curative Intent

When I meet new patients diagnosed with Stage IV metastatic melanoma, I often mention the name Jimmy Carter. It’s a name most people recognize, and his survival story is nothing short of remarkable—especially considering he will soon celebrate his 100th birthday. Like many of my patients, Carter was diagnosed with Stage IV melanoma, with metastatic …

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Exciting Advances in Frontline Treatment for Metastatic Melanoma from ASCO 2024

The American Society of Clinical Oncology (ASCO) 2024 conference was a remarkable event, bringing together leading minds in oncology to discuss the latest breakthroughs and research in cancer treatment. This year’s conference was particularly notable for the innovative approaches presented in the treatment of metastatic melanoma, a challenging and aggressive form of skin cancer. In …

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Dr. Sajeve Thomas
Dr Daniel Landau


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