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Neoadjuvant Immunotherapy Sets New Standard in Stage III Melanoma: Findings from the NADINA Trial

Stage III melanoma means the cancer has spread beyond the original tumor to nearby areas but hasn’t reached distant parts of the body. The prognosis for Stage III melanoma varies depending on several factors, including the extent of lymph node involvement, the presence of in-transit or satellite lesions, and the patient’s overall health. Treatment for …

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Why Maintaining Good Health is Essential During Clinical Trial Participation

Maintaining good health is vital for everyone, but it’s especially crucial for patients diagnosed with cancer. This becomes even more important to those participating in clinical trials, where the physical and mental demands can be significant. Ensuring balanced diet and regular exercise can play a key role in supporting your overall well-being throughout this challenging …

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Breaking Down Barriers to Cancer Care: How Oncology Nurse Navigators Light the Way

In the realm of oncology, the journey from diagnosis to treatment is often marked by a maze of medical, emotional, and logistical challenges. Oncology nurse navigators are specialized nurses who serve as a bridge between patients, their families, and the healthcare system. Our primary goal is to ensure that patients receive comprehensive, coordinated care while …

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Reflections on 13 Years at Orlando Health: Lessons Learned and the Road Ahead

As I step away from my role as a medical oncologist at Orlando Health, I find myself reflecting on the remarkable journey that has spanned the last 13 years. It’s a bittersweet moment, filled with a mix of gratitude, pride, and anticipation for what lies ahead as I finish up my last days by the …

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PERSEUS Trial Results Lead to FDA Approval of Daratumumab-VRD Regimen for Multiple Myeloma

Multiple myeloma (MM) is a type of blood cancer that originates in the plasma cells, which are a type of white blood cell found in the bone marrow. Plasma cells are responsible for producing antibodies that help fight infections. In multiple myeloma, abnormal plasma cells multiply uncontrollably, leading to a range of complications. Key Characteristics …

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From Hope to Reality: FDA Approves Tecelra, a Breakthrough Gene Therapy for Synovial Sarcoma

When it comes to battling a rare and aggressive cancer like synovial sarcoma, the treatment options have often been limited—until now. The FDA’s recent approval of Tecelra (Amafi-Cel), the first gene therapy for adults with metastatic synovial sarcoma, not only provides new hope for patients who’ve exhausted other options but also paves the way for …

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From ‘Last Resort’ to First Choice: Rethinking Clinical Trials in Cancer Care and Debunking Myths 

Deciding to join a clinical trial can feel daunting, especially with the myths and misconceptions that surround them. Let’s take a moment to clear the air and set the record straight about what clinical trials really mean for you as a patient. Myth #1: “I’m Just a Lab Rat” Contrary to popular belief, participating in …

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Managing “Scanxiety”- Coping with Anxiety Surrounding Cancer Scans

Meet Sarah, a resilient woman in her late 40s who has been battling stage IV metastatic melanoma. After enduring the uncertainties of her diagnosis, Sarah achieved a remarkable remission through immunotherapy, a victory that brought her and her loved ones immense relief. However, the journey doesn’t end there. Sarah now faces the ongoing challenge of …

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Understanding the Best Multimodal Treatment for Esophageal Adenocarcinoma: Insights from the ESOPEC Trial

Esophageal adenocarcinoma (EAC) is a malignancy with rising incidence in Western countries, largely due to increasing rates of gastroesophageal reflux disease and obesity. Despite advancements in treatment, the prognosis for EAC remains poor, with a five-year survival rate of less than 20% for advanced stages. Current management of locally advanced, resectable EAC often involves neoadjuvant …

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Exciting Advances in Frontline Treatment for Metastatic Melanoma from ASCO 2024

The American Society of Clinical Oncology (ASCO) 2024 conference was a remarkable event, bringing together leading minds in oncology to discuss the latest breakthroughs and research in cancer treatment. This year’s conference was particularly notable for the innovative approaches presented in the treatment of metastatic melanoma, a challenging and aggressive form of skin cancer. In …

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Dr. Sajeve Thomas
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